Gene Reporter Systems
ABclonal Technology Phospho-PDGFR alpha-Y754 Rabbit pAb
This gene encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. Studies suggest that this gene plays a role in organ development, wound healing, and tumor progression. Mutations in this gene have been associated with idiopathic hypereosinophilic syndrome, somatic and familial gastrointestinal stromal tumors, and a variety of other cancers.
BPS Bioscience Inc CDK1/CyclinA2, GST-Tag Recombinant, 10ug
Complex of human CDK1 (Cyclin Dependent Kinase 1) and human Cyclin A2. The two constructs are: recombinant human CDK1, full length encompassing amino acids 2-297 (end) and recombinant human Cyclin A2, full length encompassing amino acids 2-432 (end). Both constructs contain an N-terminal GST-Tag. A short peptide linker placed between GST and the protein includes a PreScission protease cleavage site. The two proteins were co-expressed in Sf9 insect cells and spontaneously formed a complex, which was affinity purified.
BIORTUS USA INC Human CDK3/CyclinE2 Protein, 100UG
Gene Name: CDK3/CCNE2. Uniprot: Q00526/O96020. Construct: GST-3C-CDK3(1-305end)/Flag-His-TEV-Cyclin E2 (S2-H404 end). Expression Host: Insect cell. Purity: 80%.
ABclonal Technology CYP2D6 Rabbit pAb
This gene encodes a cytochrome P450 enzyme, part of the monooxygenase family involved in drug metabolism and the synthesis of cholesterol, steroids, and lipids. It is located in the endoplasmic reticulum and metabolizes about 25% of commonly prescribed drugs, including antidepressants, antipsychotics, analgesics, and antiemetics. The gene is highly polymorphic, with certain alleles leading to the poor metabolizer phenotype, characterized by reduced drug metabolism. Some individuals may lack functional protein due to two null alleles, while others may have no gene copies. Individuals with the ultrarapid metabolizer phenotype may have 3 or more active gene copies. Alternative splicing of this gene results in various isoforms.
ABclonal Technology Phospho-PDGFR alpha-Y849 Rabbit pAb
This gene encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. Studies suggest that this gene plays a role in organ development, wound healing, and tumor progression. Mutations in this gene have been associated with idiopathic hypereosinophilic syndrome, somatic and familial gastrointestinal stromal tumors, and a variety of other cancers.
ABclonal Technology CYP2D6 Rabbit pAb
This gene encodes a cytochrome P450 enzyme, part of the monooxygenase family involved in drug metabolism and the synthesis of cholesterol, steroids, and lipids. It is located in the endoplasmic reticulum and metabolizes about 25% of commonly prescribed drugs, including antidepressants, antipsychotics, analgesics, and antiemetics. The gene is highly polymorphic, with certain alleles leading to the poor metabolizer phenotype, characterized by reduced drug metabolism. Some individuals may lack functional protein due to two null alleles, while others may have no gene copies. Individuals with the ultrarapid metabolizer phenotype may have 3 or more active gene copies. Alternative splicing of this gene results in various isoforms.
Bioss KD-Validated Mevalonate Kinase
Mevalonate Kinase Primary Antibody Unconjugated Public Immunogen Range 320-370/396 Host Species Rabbit Target Species Human Rat Clonality Monoclonal Applications WB IC Concentration Lot dependent Size 50 ul Storage Buffer Supplied in PBS (pH 7 4) containing 50% glycerol and 0 02% sodium azide
Sigma Aldrich Fine Chemicals Biosciences KDR Protein active 10 18
human KDR expressed by baculovirus in Sf21 insect cells
Genscript Corporation VEGF R2/KDR mFc Chimera Human
Tyrosine-protein kinase that acts as a cell-surface receptor for VEGFA VEGFB and PGF and plays an essential role in the development of embryonic vasculature the regulation of angiogenesis cell survival cell migration macrophage function chemotaxis and cancer cell invasion The tyrosine kinase receptor vascular endothelial growth factor receptor 2 (VEGFR2) is a key regulator of angiogenesis
Gold Biotechnology Inc ProBlock™ Gold Protease Inhibitor Cocktail [100X] 10 mL
Due to the optimized concentration of the various inhibitors, the ProBlock™ Gold shows excellent inhibition of protease activities and is therefore suitable for the protection of proteins during purification from animal tissues, plant tissues, yeast and bacteria. ProBlock™ Gold contains both irreversible and reversible protease inhibitors to inhibit serine, cysteine and other proteases. An separate bottle of EDTA is provided to inhibit metalloproteases.
Cayman Chemical PKC Pseudosubstrt InHBTo1mg
A synthetic peptide that corresponds to amino acid residues of the pseudosubstrate domain of PKCθ
Cayman Chemical ADP-GlucosesodIum salt 10mg
An immediate precursor used in the biosynthesis, by glucose addition, of storage polysaccharides in plants, green algae, and cyanobacteria, as well as structural polysaccharides in certain bacteria
Cell Biolabs Inc QuickTiter™ AAV Quantitation Kit, 20 assays
Cell Biolabs' QuickTiter™ AAV Quantitation Kit provides an ultra-fast 45-60 minute procedure that measures physical titer of unpurified AAV-2 or AAV-DJ, or of purified virus from any AAV serotype, via the viral nucleic acid content. Quantitation is performed on a 96-well fluorescence based plate reader. The kit provides sufficient reagents for 20 assays.